Click chemistry on hair 2

Here is the click chemistry to be applied in the salons :))

Click chemistry on hair 1

Poly. Chem. 2012, 3, 1461


Finally, click chemistry goes to cosmetic industry,  the fastest-growing industry of all? 


Well, sure thing is that you do need fast, mild, high-yielding, failure-proof, safe reactions 
to be happening in hair salons (on the head). Doe that sound like a "perfect" reaction, in the spirit of click chemistry?


Here comes an interesting one applying two types of thiol-ene click chemistry on hair.


1. Polymerisation of mixed acrylates produced the polymer with acrylate terminal alkene 
and allyl internal alkenes  
2. Thiol-ene click chemistry produced conjugates between polymer terminal alkene and thiol 
groups exposed from hair alpha-keratin
3. Thiol-ene click chemistry produced modification between polymer internal alkene and thiol 
groups from dye -------  or any other fun stuff.

Branched Y-Shaped DNA by Click Chemistry

Bioconjugate Chem., 2012, 23 (4), pp 856–870
DOI: 10.1021/bc300013k

Stepwise and double click chemistry produced branched Y-shaped three-armed DNA. 
Hybridization of branched DNA with complementary oligonucleotides yielded supramolecular assemblies / nanostructures.