This is to respond to a reader's excellent request - why not put together a list of vendors of click chemistry reagents, with active links, to make click chemistry a click away? Here it goes:
http://www.sigmaaldrich.com/chemistry/chemical-synthesis/technology-spotlights/click.html
http://www.invitrogen.com/site/us/en/home/Products-and-Services/Applications/Cell-Analysis/Labeling-Chemistry/Click-chemistry-Labeling-and-Detection.html
http://www.lumiprobe.com/c/click-chemistry-reagents
http://www.clickchemistrytools.com/Products.html
http://www.creativepegworks.com/Click_PEG_derivatives.html
http://www.activemotif.com/catalog/681/fluorescent-tools-for-click-chemistry
http://www.jenabioscience.com/cms/en/1/browse/1379_click_chemistry_reagents.html
http://www.idtdna.com/pages/decoded/decoded-articles/find-out-first-2/decoded/2011/09/12/click-chemistry
http://www.iba-go.com/naps/naps_p_edcc.html
http://www.enamine.net/index.php?option=com_content&task=view&id=127
http://www.berryassoc.com/clickmates.asp
http://www.glenresearch.com/GlenReports/GR23-13.html
http://www.anaspec.com/products/promotions.asp?id=55&col=2&row=2
http://www.quantabiodesign.com//
http://www.primetech.by/en/biocon_click.html
http://www.gfschemicals.com/statics/documents/randd/randd2a82dd80b59a4d08a177471f6aadf1a6.html
http://www.baseclick.eu/products.php
http://www.setabiomedicals.com/click-chemistry.php
http://www.interchim.fr/ft/F/FY2780.pdf
http://www.amtechpl.com/docs/AMT%20Click%20Chemistry%20Fact%20Sheet_V1%200_20111129.pdf
http://www.chemgenes.com/products.php
http://www.iris-biotech.de/pegylation/peg-azides-for-click-chemistry.html
http://www.piercenet.com/browse.cfm?fldID=78C8CEF4-5056-8A76-4E62-B899CF83E209
http://www.caymanchem.com/app/template/productQualifiers%2CProductQualifier.vm/productqualifier/click-chemistry
http://www.cambio.co.uk/1160/66/products/azide-tags/
http://www.fluorous.com/groups/174-10.html
http://www.metabion.com/products/click.php
http://www.bachem.com/newsletter/July_2011_New_Products.html
http://pepnet.com/shoppingusers/PdfDocument.aspx?FileName=pepnet242.pdf
http://www.cyanine.com/life-science/applications/click-chemistry
http://www.prochimia.com/compound_description.php?prod_id=8
http://proteinslides.com/click.html
A few notes:
1. No way it is exclusive - please let me know the ones I have missed so I can add them in future updates.
2. Chances are the addresses would change over time - the best way then is to copy the company link to your web browser and click to get to the vendor followed by search that website.
3. It was stated why "vendors matter" in a separate post.
Saturday, December 10, 2011
Sunday, December 4, 2011
Diels-Alder Click Chemistry for Tissue Engineering Hydrogel
Biomacromolecules, 2011, 12 (3), pp 824–830
Diels-Alder cycloaddition satisfies click chemistry criteria and features elegant multiple-bond formation in a single step in very high yeild. Here a furan diene was installed onto the natural polymer hyaluronic acid and it was cross-linked by a bifunctional dienophile, dimaleimide poly(ethylene glycol) to form the cytocompatible hydrogels for potential soft tissue engineering. The click reaction runs smoothly in aqueous buffer without initiator, catalyst, or other coupling reagents.
Diels-Alder cycloaddition satisfies click chemistry criteria and features elegant multiple-bond formation in a single step in very high yeild. Here a furan diene was installed onto the natural polymer hyaluronic acid and it was cross-linked by a bifunctional dienophile, dimaleimide poly(ethylene glycol) to form the cytocompatible hydrogels for potential soft tissue engineering. The click reaction runs smoothly in aqueous buffer without initiator, catalyst, or other coupling reagents.
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