Wednesday, December 19, 2012

LI-COR offers click chemistry reagents / dyes

Li-Cor, the company of "environmental and biotechnology research systems", started to offer click chemistry reagents

They combined click chemistry with its unique long-wavelength Infrared dyes. Dyes include: IRDye 800CW, TRDye 680RD, IRDye 650. Click chemistry gourps include: dibenzocyclooctyne (DBCO), azide and alkyne. The coupling of above (3x3) generated 9 reagents - for click chemistry in the field of in vitro or in vivo labeling and tracking of biomolecules. Options are available with copper-catalyzed and copper-free versions of click chemistry. 

A webinar is provided for viewers.

Sunday, December 16, 2012

Nicholas Turro and the legacy

Nicholas Turro died on November 24, 2012. 

Many of us learned from his photochemistry book, watched his photochemistry videos, met him in person, listened to his presentation on supramolecular photochemistry, and read his recent work on the applications of click chemistry. 

Dr Turro is a truly classy figure in many ways: one of the giants of modern photochemistry;  leader and trail-blazer of creative research in new fields; excellent teacher, educator and lecturer to many levels; superb book writer and natural presenter; father of the large "Turro" academic family; member of NAS and AAAS; recipient of many elite awards. 

A big loss and many will miss him. 


Click chemistry in single molecule sequencing

Well, click chemistry has come to single molecule sequencing, one of the hottest spots in modern biotechnology. Pacific Biosciences has demonstrated the sensitive and specific single molecule sequencing of 5-hydroxylmethylcytosine in DNA. Here it is summarized:

Nature Methods, 2012, 9(1), 75