Saturday, November 27, 2010

First Thanksgiving of Click Chemistry

It is this time of the year and Click Chemistry has seen its first Thanksgiving. We celebrate it and express great respect and gratitude to the readers and workers in the field of click chemistry.

It is not only useful and convinent chemistry, it is fun and exciting chemistry. Only the future will tell how widespread and unique a certain type of reaction (such as click chemistry) actually penetrates into many other branches of sciences. We are very positive because it is only the starting point of the endless possibilities. 

Happy Thanksgiving everyone! 

Sunday, November 14, 2010

BASF press release on DNA labeling via click chemistry

BASF press release 10/4/2010

Baseclick GmbH, a spin-off from BASF SE and Ludwig-Maximilians-Universit├Ąt Munich, has signed licensing agreements with Integrated DNA Technology (IDT), Ella Biotech and metabion to provide click chemistry labeling of DNA. European Patent Office has granted the this patent to baseclick GmbH effective on 9/1/2010.

Based on Sharpless click chemistry and developed by Prof. Thomas Carell of Ludwig-Maximilians-Universit├Ąt Munich, Germany, the baseclick technology allows labeling multiple dyes on DNA strands in a sequence-specific manner. Baseclick GmbH has obtained a worldwide license for click chemistry from The Scripps Research Institute.

Applications include analyses for pathogens and detection of mutations in human, animal and plant genomes. A related report is available "Notable oligonucleotide modification using click chemistry".