Sunday, February 13, 2011
Setting standards for polymer click chemistry
Angew Chem. Int. Ed. 2011, 50, 60-62. DOI: 10.1002/anie.201003707
A group of polymer click chemistry leaders have tried to set the standards for the field - and for the terminology "polymer click chemistry" to be meaningful.
To add a few other points. Polymer chemistry has been using the most efficient reactions for a long time, before the click chemistry philosophy. Core values of click chemistry need to be defended - many published claims are not in the spirit of click chemistry.Click chemistry is not equal to "efficient" or "successful". Click chemistry should meet the set high standards and remain fluid as a philosphy. Exceptions should be allowed in extremely challenging complex systems, such as "spying on" the activities inside a live cell.