Sunday, June 19, 2011

Click chemistry in RNA - marrying Uridine and Azidocoumarin

Marrying Uridine and Azidocoumarin provided a multifunctional sensing moiety in RNA which allows photoaffinity labeling and click chemistry. The key elements are summarized in the drawing below.
Mark Helm et al, Nucleic Acids Research, doi:10.1093/nar/gkr449 published June 6, 2011

1 comment:

  1. Keep up the good work. Your blog has a lot of very useful information. Maybe you can link some of the patents and sigma catalogues to allow us to "click it".